Vaccines, biological substances from pathogenic microorganisms such as viruses or bacteria, train the immune system to recognize and react to specific pathogens to prevent the spread of diseases.
Vaccines, biological substances from pathogenic microorganisms such as viruses or bacteria, train the immune system to recognize and react to specific pathogens to prevent the spread of diseases.
Wet milling is a vital process in vaccine production. It disrupts the cells of the pathogenic microorganisms so the pathogens undergo degradation and inactivation to expose and release the antigens. When the antigens are reduced to the nanoscale or microscale through wet milling or cell homogenization, they can more readily activate immune cells, triggering responses with fewer side effects. Wet grinding can also help improve the stability of vaccine components by preventing the aggregation of the active ingredients, which can otherwise diminish the vaccine’s efficacy.
LONGLY Group provides necessary technologies for cell disruption. Our bead mill and high pressure homogenizers designed for vaccine production, can open the cells without damaging the biological substances.